Breakthrough Zygomycosis and Voriconazole

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منابع مشابه

Breakthrough zygomycosis and voriconazole.

cines and the template described in An-derson and Hanson [2]. Blower falsely claims (e.g., see [3], p. 118) that her 1993 and 1994 articles included , to quote, " the first transmission model of HIV vaccines to assess the potential epidemic-level impact of imperfect vaccines. " This is incorrect—the 1991 Nature article by Anderson et al. was the first. To the Editor—Zygomycosis is an inva-sive ...

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Breakthrough zygomycosis during voriconazole treatment for invasive aspergillosis.

Voriconazole is active against Aspergillus and other filamentous fungi, but it has no activity against Zygomycetes. Iowa and Boston groups reported an increase in the incidence of zygomycosis in patients given prophylactic voriconazole. Long-term use of voriconazole might exert selective pressure for growth of resistant organisms however, reviews of data from several transplantation centers sho...

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Breakthrough zygomycosis on posaconazole prophylaxis after allogeneic stem cell transplantation.

Antifungal prophylaxis with posaconazole (POS) has been shown to decrease the mortality associated with invasive fungal infections in high-risk patients. We report on a patient, with severe graft-versus-host disease after allogeneic stem cell transplantation, who developed proven pneumonia due to Rhizopus microsporus after 40 days of POS prophylaxis (fasting serum levels: 691-904 ng/mL). Despit...

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Breakthrough fungal infections in stem cell transplant recipients receiving voriconazole.

Infection with voriconazole-resistant fungi may become problematic, because organisms with decreased susceptibility have been noted. Breakthrough fungal infections occurred in 13 of 139 patients who received voriconazole at our center during the period of September 1998 through September 2003. Zygomycetes were found in 6 patients, and Candida glabrata bloodstream infection occurred in 4 patient...

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Breakthrough zygomycosis following empirical caspofungin treatment: report of two patients with leukemia and literature review

Breakthrough zygomycosis are increasingly reported life-threatening complications among patients with hematological malignancies, especially since the use of broad spectrum antifungal treatments like voriconazole. We report two cases of breakthrough zygomycosis after caspofungin exposure, with a review of literature.

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2005

ISSN: 0022-1899,1537-6613

DOI: 10.1086/444433